Renal denervation is a minimally invasive catheter-based procedure to treat hypertension. The procedure is generally opted in cases where drug therapies are unable to provide relief. It includes ablation of the nerves of renal artery wall by the use of radiofrequency pulses or ultrasound. This reduces sympathetic kidney activity, which further leads to a reduced blood pressure.

The Global renal denervation market was $197 million in 2015 and is expected to reach $3,153 million by 2022 with a CAGR of 48.5%. The market is driven by many factors such as changes in lifestyle, which leads to resistant hypertension, increasing prevalence of hypertension, technological advancements to develop alternative technologies (such as micro-infusion) for renal denervation systems. However, stringent regulatory norms for renal denervation devices, and unfavorable reimbursements for renal denervation procedure have restricted the market growth.

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Segment Review:

According to the analysis carried out for each segment, the Symplicity Renal Denervation System accounted for the largest market share in 2015. Symplicity is the major and most frequently used product of the renal denervation market. According to the CIRSE Member Survey (2013), Symplicity is used by approximately 78% of the European hospitals. This system is generally preferred as it delivers low level of RF energy and thus reduces the potential risks associated with high levels of RF radiation on body tissues. Above all, the device provides a minimally invasive method to treat excessive hypertension. In addition, the Vessix Renal Denervation System is expected to have the highest growth rate as it uses a full-color graphic user interface that increases the accuracy and operation of the device. This feature enables the Vessix system to be a preferred system by physicians as well as patients.

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Australian Renal Denervation Market Snapshot:

Australia is considered to be a potential market for the growth of renal denervation devices in the coming future. The renal denervation systems, such as Symplicity Renal Denervation System and Vessix Renal Denervation System have received regulatory approvals from Therapeutic Goods Administration (TGA) in the region and are available for sales. The companies in this market have launched clinical trials in this region to check the effect of devices over patients’ health and test the device efficacy. In this regard, Medtronic launched Symplicity HTN-1, Symplicity HTN-2, and Symplicity-HF trials in Australia as well as some other geographical locations. Moreover, St. Jude Medical, Inc. also launched EnligHTN I, EnligHTN II, and EnligHTN III trials in many regions including Australia. Thus, the leading players are focusing on expansion in the Australian economy, which will lead to market growth in this region.

Top Impacting Factors

Prevalence of hypertension

Hypertension is one of the most prevalent diseases in the world. According to the 2012 article of Journal of Hypertension, atrial hypertension affects approximately 25% of the global population. According to the 2011 statistics provided by the American Heart Association, approximately 33% (nearly 70 million people) of the U.S. adult population is suffering from high blood pressure.

Changing lifestyle of people

Major lifestyle changes such as smoking, alcohol consumption, increased consumption of ready to consume food products, and lack of physical activity of people increases the chance for hypertension and high blood pressure. Studies have revealed a clear link between the consumption of high levels of salt and rise in blood pressure.

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